The ISPNE maintains a membership of approximately 450 active members throughout the world. Although a majority of members are from North America and Europe, there is representation from most world regions. Regular members receive the official journal of the Society, Psychoneuroendocrinology published by Elsevier. The journal is also available throughout the world at some 600 subscribing institutions and libraries.

The Society membership is approximately evenly divided between basic research scientists holding the Ph.D. or equivalent degree and clinical researchers holding the M.D. or equivalent degree; this division is reflected by the scientific content of both the Journal and the annual Congress proceedings. In the years since the inception of the society, annual meetings have been held every year, except for 1989.

Membership in the Society is open to those professionals meeting criteria as set forth in the bylaws. 2007 membership fees include reduced registration fees for the annual meeting.

Members:
U.S. $210 per year for those who wish to receive both print and electronic copy of the Journal
U.S. $165 per year for those who wish to receive only the electronic copy of the Journal

Young Investigators:
U.S. $45 for the electronic copy (no print copy of the Journal will be offered)